Purified Anti-Mouse CD127/IL-7RA Antibody(A7R34), Rat, Monoclonal

Purified Anti-Mouse CD127/IL-7RA Antibody(A7R34), Rat, Monoclonal
Artikelnummer
ELSE-AB-F1023A-25
Verpackungseinheit
25 µg
Hersteller
Elabscience Biotechnology

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Abbreviation: CD127

Target Synonym: Interleukin-7 receptor subunit alpha;Il7r;IL-7 receptor subunit alpha;IL-7R subunit alpha;IL-7R-alpha;IL-7RA;CD127;

Conjugation: Unconjugated

Usage: Each lot of this antibody is quality control tested by flow cytometric analysis. For flow cytometric staining, the suggested use of this reagent is ≤ 1.0 µg per 10^6 cells in 100 µL volume or 100 µL of whole blood. It is recommended that the reagent be titrated for optimal performance for each application.

Clone NO.: A7R34

UNIProt ID: P16872

Background: CD127 is a 60-90 kD type I transmembrane glycoprotein also known as IL-7 receptor α chain or IL-7Rα. It forms a heterodimer with the common γ chain (γc or CD132) which is shared with the receptors for IL-2, IL-4, IL-9, IL-13, IL-15, and IL-21. CD127 is expressed on immature B cells through early pre-B stage, thymocytes (except CD4/CD8 double positive thymocytes), peripheral T cells, and bone marrow stromal cells. CD127 has been reported to be an useful marker for identifying memory and effector T cells. The ligation of IL-7 with its receptor is important for stimulation of mature and immature T cells as well as immature B cells proliferation and development.

Concentration: 0.5 mg/mL
Mehr Informationen
Artikelnummer ELSE-AB-F1023A-25
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer ELA-E-AB-F1023A-25
Green Labware Nein
Verpackungseinheit 25 µg
Mengeneinheit STK
Reaktivität Mouse (Murine)
Methode Flow Cytometry
Isotyp Rat IgG2a κ
Human Gene ID 16197
Wirt Rat
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