Solubility: Soluble in DMSO at 200 mg/ml; soluble in ethanol at 200 mg/ml; very poorly soluble in water
Appearance: Crystalline solid
PubChem CID: 9849735
Scientific Background: PX 866 is a wortmannin derivative that inhibits purified phosphoinositide (PtdIns)-3-kinase and. PX 866 has been shown to inhibit tumor growth by blocking the PI 3-kinase pathway and cell motility.
References: 1. Ihle N.T., et al. (2004). Mol. Cancer. Ther. 3(7): 763–772.2. Gwak H.S., et al. (2011). Int. J. Cancer. 128(4): 787–796.
Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.