QKI Antibody, Clone N147/6: FITC

Mouse Anti-Human QKI (pan) Monoclonal IgG2b

Target: QKI

Conjugate: FITC

Product Type: Monoclonal

Clone Number: N147/6 (Formerly sold as S147-6)

Immunogen: Fusion protein amino acids 1-341 (full-length) of human QKI-5. Mouse: 100% identity (341/341 amino acids identical). Rat: 99% identity (339/341 amino acids identical) >90% identity with QKI-6, QKI-7 and QKI-7b.

Swiss-Prot: Q96PU8

Purification: Protein G Purified

Storage Buffer: PBS pH 7.4, 50% glycerol, 0.1% sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Detects ~36-38kDa.

Cellular Localization: Cytoplasm,Nucleus

Scientific Background: QKI is also called Protein Quaking or HqkI. QKI is an RNA-binding protein that plays a central role in myelinization. QKI acts by regulating pre-mRNA splicing, mRNA export, mRNA stability and protein translation, and is itself, regulated by alternative splicing. QKI is expressed in the frontal cortex of brain, but is shown to be down-regulated in the brain of schizophrenic patients.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-467D-FITC
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-467D-FITC
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG2b
• Human Gene ID: 9444
• Wirt: Mouse