Rabbit anti-CDC20 IHC Antibody, Affinity Purified

Stock Concentration: 500 µg/ml

Conjugate Type: Unconjugated

Buffer: Tris-buffered Saline containing 0.1% BSA and 0.09% Sodium Azide

Shelf Life: 1 year from date of receipt

Protein ID: NP_001246.2

Uniprot ID: Q12834

Background: CDC20 is a WD repeat containing cell cycle-regulator that binds to and activates the ubiquitin-ligase activity of the APC/c (anaphase-promoting complex/cyclosome). APC/c ubiquitinating activity is responsible for the degradation of securin and cyclin B that prompts the onset of anaphase and exit from mitosis. CDC20 has also been reported to form a complex with histone deacetylases and can function as a transcriptional repressor involved in cell cycle arrest. As a regulator of APC/c activity, CDC20 plays a key role in the spindle-assembly checkpoint.

Immunogen: Between 50 and 100

• Artikelnummer: BEYIHC-00232
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: IHC-00232
• Green Labware: Nein
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine)
• Klonalität: Polyclonal
• Methode: Immunohistochemistry
• Isotyp: Whole IgG
• Human Gene ID: 991
• Wirt: Rabbit