Rabbit anti-Hepassocin/FGL1 Recombinant Monoclonal Antibody (BLR210K)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_004458.3

Uniprot ID: Q08830

Background: Hepassocin, also known as Fibrinogen-like 1 (FGL1), is a member of the fibrinogen family whose members share a fibrinogen domain at their C-termini. However, it lacks the platelet-binding site, cross-linking region and thrombin-sensitive site which are necessary for fibrin clot formation. Hepassocin/FGL1 is secreted by hepatocytes and may play a role in the development of hepatocellular carcinomas. Hepassocin/FGL1 is an immune suppressive molecule that inhibits antigen-specific T-cell activation by acting as a major ligand of LAG3 [taken from NCBI Entrez Gene (Gene ID: 2267)].

Immunogen: Residues 18-312 (full length)

• Artikelnummer: BEYA700-210CF
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A700-210CF
• Green Labware: Nein
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Immunoprecipitation, Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: Whole IgG
• Human Gene ID: 2267
• Wirt: Rabbit