Rabbit anti Human Adiponectin Receptor 2

Rabbit anti Human Adiponectin Receptor 2, Polyclonal
Artikelnummer
EXAX1699P
Verpackungseinheit
100 µg
Hersteller
Exalpha Biologicals Inc

Verfügbarkeit: wird geladen...
Preis wird geladen...
Background: ADR2 functions as a receptor for globular and full-length adiponectin (APM1), which is an essential hormone secreted by adipocytes that acts as an antidiabetic. ADR2 is also probably involved in metabolic pathways that regulate lipid metabolism such as fatty acid oxidation. ADR2 mediates an increase in AMPK, PPARA ligand activity, fatty acid oxidation and glucose uptake by adiponectin and has some intermediate-affinity receptor activity for both globular and full-length adiponectin. ADR2 may form homo and heteromultimers.

Positive Control: Colon, Hippocampus, and Trachea.

Purification Method: Ammonium sulfate precipitation.

Source: Rabbits were immunized with a synthetic peptide near the C terminus of human adiponectin receptor 2 proteins.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

References: 1. Strausberg R.L., Feingold E.A., Grouse L.H., Derge J.G., Klausner R.D., Collins F.S., Wagner L., Shenmen C.M., Schuler G.D., Altschul S.F., Zeeberg B., Buetow K.H., Schaefer C.F., Bhat N.K., Hopkins R.F., Jordan H., Moore T., Max S.I., Wang J., , Marra M.A.; Generation and initial analysis of more than 15,000 full-length human and mouse cDNA sequences.; Proc. Natl. Acad. Sci. U.S.A. 99:16899-16903(2002).
2. Yamauchi T., Kamon J., Ito Y., Tsuchida A., Yokomizo T., Kita S., Sugiyama T., Miyagishi M., Hara K., Tsunoda M., Murakami K., Ohteki T., Uchida S., Takekawa S., Waki H., Tsuno N.H., Shibata Y., Terauchi Y., Froguel P., , Kadowaki T.; Cloning of adiponectin receptors that mediate antidiabetic metabolic effects.; Nature 423:762-769(2003).

UniProt: Q86V24.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.
Mehr Informationen
Artikelnummer EXAX1699P
Hersteller Exalpha Biologicals Inc
Hersteller Artikelnummer X1699P
Green Labware Nein
Verpackungseinheit 100 µg
Mengeneinheit STK
Reaktivität Human
Klonalität Polyclonal
Methode Western Blotting, ELISA
Wirt Rabbit
Produktinformation (PDF) Download
MSDS (PDF) Download