Clone Number: SP4
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Cyclins are proteins that govern transitions through distinct phases of the cell cycle by regulating the activity of the cyclin-dependent kinases. Cyclin D1, one of the key cell cycle regulators, is a putative proto-oncogene found in a wide variety of human neoplasms. This antibody is useful for distinguishing mantle cell lymphomas (cyclin D1 positive).
References: Aagaard, L, et al. International J of Cancer 1995;61(1):115-120/Bartkova, J, et al. Cancer Research 1995;55:949-956/Bartkova, J, et al. Oncogene 1995’10(4):775-778