Rabbit anti Human Degenerative Spermatocyte Homolog 1 (DEGS1)

Rabbit anti Human Degenerative Spermatocyte Homolog 1 (DEGS1), Polyclonal, IgG

Background: The product of the DEGS1 gene is a member of the membrane fatty acid (sphingolipid delta 4) desaturase family. Reported to function by inserting double bonds at delta 4 position in fatty acids. DEGS1 is an intracellular enzyme. Overexpression of this gene inhibited biosynthesis of the EGF receptor, suggesting a possible role of a fatty acid desaturase in regulating biosynthetic processing of the EGF receptor. Two splice variants have been identified.

Positive Control: Placenta, normal human brain

Immunogen: Synthetic peptide derived from the human DEGS1 protein

Purification Method: Antigen Immunoaffiinity Purification

Concentration: Lot specific, see vial

Formulation: Provided as solution in Tris buffered saline with 0.08% sodium azide

References: 1. Cadena, D.L., et al. 'The product of the MLD gene is a member of the membrane fatty acid desaturase family: overexpression of MLD inhibits EGF receptor biosynthesis.; Biochemistry 36:6960-6967(1997).2. Ternes, P., et al. 'Identification and characterization of a sphingolipid delta 4-desaturase family.; J. Biol. Chem. 277:25512-25518(2002).

UniProt: O15121 (Human)Q5XIF5 (Rat)O09005 (Mouse)

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX2383P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X2383P
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit
• Konjugat: Unconjugated