Rabbit anti Human Gi alpha 1/2

Rabbit anti Human Gi alpha 1/2, Polyclonal, IgG

Background: GTP-binding proteins (G-proteins) play a critical role in signal transduction by coupling receptors to effectors. The intracellular consequences of G-protein activation include second messenger generation, protein phosphorylation, ion channel activation, gene induction, cell growth, and differentiation. Gi belongs to the pertussis toxin sensitive G-proteins. Gi consists of three different subtypes of -subunits ( i1, i2 and i3).

Positive Control: IMR-5 cells or brain.

Source: Rabbits were immunized with a peptide corresponding to amino acids 345-354 of Gi 1 and 346-355 of Gi 2.

References: 1. Li X, et al. Pertussis toxin-sensitive G protein alpha-subunits: production of monoclonal antibodies and detection of differential increases on differentiation of PC12 and LA-N-5 cells. J. Neurochem. 1995, 64, 1107-1117.

UniProt: P04899.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX1595P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X1595P
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus), Cow (Bovine)
• Klonalität: Polyclonal
• Methode: Western Blotting
• Isotyp: IgG
• Wirt: Rabbit