Rabbit anti Human Ribonucleoside-diphosphate reductase, large subunit (RRM1)

Rabbit anti Human Ribonucleoside-diphosphate reductase, large subunit (RRM1), Polyclonal, Ig

Background: This protein is one of two non-identical subunits that constitute ribonucleoside-diphosphate reductase, an enzyme essential for the production of deoxyribonucleotides prior to DNA synthesis in the S phase of dividing cells. The gene for RRM1 is, along with several others, located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region are associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocrotical carcinoma, and lung, ovarian, and breast cancer. RRM1 plays an important role in malignancies and disease that involve this region.

Immunogen: Synthetic peptide derived from the human RRM1 protein.

Purification Method: Antigen Immunoaffinity Purification.

Formulation: Provided as solution in phosphate buffered saline with 0.08% sodium azide.

UniProt: P23921.

Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals.

• Artikelnummer: EXAX2735P
• Hersteller: Exalpha Biologicals Inc
• Hersteller Artikelnummer: X2735P
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Polyclonal
• Methode: Western Blotting, ELISA, Immunohistochemistry
• Isotyp: Ig
• Wirt: Rabbit