Rabbit anti-NCAM-1/CD56 Recombinant Monoclonal Antibody (BLR152J)

Stock Concentration: 1000 µg/ml

Conjugate Type: Unconjugated

Buffer: Borate Buffered Saline (BBS) pH 8.2 with 0.09% Sodium Azide, BSA-Free

Shelf Life: 1 year from date of receipt

Protein ID: NP_000606.3

Uniprot ID: P13591

Background: NCAM1, is a cell adhesion protein of the immunoglobulin superfamily that is involved in cell-to-cell interactions as well as cell-matrix interactions during development and differentiation. It plays a role in the development of the nervous system by regulating neurogenesis, neurite outgrowth, and cell migration. NCAM1 is also involved in the expansion of T lymphocytes, B lymphocytes and natural killer (NK) cells which play an important role in immune surveillance. One prominent isoform NCAM1, known as cell surface molecule CD56, plays a role in several myeloproliferative disorders such as acute myeloid leukemia and differential expression of this gene is associated with differential disease progression. For example, increased expression of CD56 is correlated with lower survival in acute myeloid leukemia patients. [taken from NCBI Entrez Gene (Gene ID: 4684)].

Immunogen: Residues 20-318 (ECD)

• Artikelnummer: BEYA700-152CF
• Hersteller: Bethyl Laboratories
• Hersteller Artikelnummer: A700-152CF
• Green Labware: Nein
• Verpackungseinheit: 100 µl
• Mengeneinheit: STK
• Reaktivität: Human
• Klonalität: Monoclonal
• Methode: Western Blotting, Immunohistochemistry, Immunocytochemistry
• Isotyp: Whole IgG
• Human Gene ID: 4684
• Wirt: Rabbit