English
Rabbit anti-rat Thy-1/CD90
Rabbit anti-rat Thy-1/CD90, Polyclonal, Clone: Polyclonal
Artikelnummer
NORMUB2058
Verpackungseinheit
0,1 ml
Hersteller
Nordic-MUbio
Verfügbarkeit:
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Clone: Polyclonal
Background: Thymocyte-1 antigen (Thy-1), also known as CD90, is a glycophosphatidylinositol (GPI)-anchored cell surface glycoprotein that is a member of the immunoglobulin superfamily. Expression of Thy-1, originally identified as a marker of thymocyte differentiation in mice, has been found to vary between species. In rats, unlike mice, Thy-1 is expressed on bone marrow cells but not on peripheral T-cells. In both mice and rats, Thy-1 is abundantly expressed on thymocytes and neuronal cells and to a lesser extent on fibroblasts, myofibroblasts, vascular endothelial cells, mammary glands and other non-lymphoid tissues. In many tissues the level of Thy-1 expression changes during cell differentiation. The exact function of Thy-1 has not been fully determined but studies suggest that Thy-1 may be an important regulator of cell-cell and cell-matrix interactions due to its involvement in a range of biological processes including cell growth and differentiation, cell adhesion and migration, apoptotic signalling and tumour suppression.
Source: Thy-1 antibody is a rabbit polyclonal antiserum obtained from rabbits immunised with purified Thy-1 derived from rat brain.
Specificity: Thy-1 antiserum is directed against rat thymocyte-1 antigen (Thy-1) and also reacts with mouse Thy-1.
Formulation: Each vial contains 100µl polyclonal antiserum containing 0.02% sodium azide.
References: 1. Barclay AN, Letarte-Muirhead M, Williams AF. (1975) Purification of the Thy-1 molecule from rat brain. Biochem J. 151:699-706.2. Letarte-Muirhead M, Barclay AN, Williams AF. (1975) Purification of the Thy-1 molecule, a major cell-surface glycoprotein of rat thymocytes. Biochem J. 151:685-97.3. Barclay AN, Hydén H. (1978) Localization of the Thy-1 antigen in rat brain and spinal cord by immunofluorescence. J Neurochem. 31:1375-91.4. Barclay AN. (1979) Localization of the Thy-1 antigen in the cerebellar cortex of rat brain by immunofluorescence during postnatal development. J Neurochem. 32:1249-57.5. Barclay AN, Hydén H. (1979) Localization of the Thy-1 antigen by immunofluorescence on neurons isolated from rat brain. J Neurochem. 32:1583-86.
UniProt: UniProt: P01830 (Rat), P01831 (Mouse)
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
Background: Thymocyte-1 antigen (Thy-1), also known as CD90, is a glycophosphatidylinositol (GPI)-anchored cell surface glycoprotein that is a member of the immunoglobulin superfamily. Expression of Thy-1, originally identified as a marker of thymocyte differentiation in mice, has been found to vary between species. In rats, unlike mice, Thy-1 is expressed on bone marrow cells but not on peripheral T-cells. In both mice and rats, Thy-1 is abundantly expressed on thymocytes and neuronal cells and to a lesser extent on fibroblasts, myofibroblasts, vascular endothelial cells, mammary glands and other non-lymphoid tissues. In many tissues the level of Thy-1 expression changes during cell differentiation. The exact function of Thy-1 has not been fully determined but studies suggest that Thy-1 may be an important regulator of cell-cell and cell-matrix interactions due to its involvement in a range of biological processes including cell growth and differentiation, cell adhesion and migration, apoptotic signalling and tumour suppression.
Source: Thy-1 antibody is a rabbit polyclonal antiserum obtained from rabbits immunised with purified Thy-1 derived from rat brain.
Specificity: Thy-1 antiserum is directed against rat thymocyte-1 antigen (Thy-1) and also reacts with mouse Thy-1.
Formulation: Each vial contains 100µl polyclonal antiserum containing 0.02% sodium azide.
References: 1. Barclay AN, Letarte-Muirhead M, Williams AF. (1975) Purification of the Thy-1 molecule from rat brain. Biochem J. 151:699-706.2. Letarte-Muirhead M, Barclay AN, Williams AF. (1975) Purification of the Thy-1 molecule, a major cell-surface glycoprotein of rat thymocytes. Biochem J. 151:685-97.3. Barclay AN, Hydén H. (1978) Localization of the Thy-1 antigen in rat brain and spinal cord by immunofluorescence. J Neurochem. 31:1375-91.4. Barclay AN. (1979) Localization of the Thy-1 antigen in the cerebellar cortex of rat brain by immunofluorescence during postnatal development. J Neurochem. 32:1249-57.5. Barclay AN, Hydén H. (1979) Localization of the Thy-1 antigen by immunofluorescence on neurons isolated from rat brain. J Neurochem. 32:1583-86.
UniProt: UniProt: P01830 (Rat), P01831 (Mouse)
Caution: This product is intended FOR RESEARCH USE ONLY, and FOR TESTS IN VITRO, not for use in diagnostic or therapeutic procedures involving humans or animals. This datasheet is as accurate as reasonably achievable, but Nordic-MUbio accepts no liability for any inaccuracies or omissions in this information.
| Artikelnummer | NORMUB2058 |
|---|---|
| Hersteller | Nordic-MUbio |
| Hersteller Artikelnummer | MUB2058 |
| Green Labware | Nein |
| Verpackungseinheit | 0,1 ml |
| Mengeneinheit | STK |
| Reaktivität | Mouse (Murine), Rat (Rattus) |
| Klonalität | Polyclonal |
| Methode | Immunohistochemistry (frozen), Immunocytochemistry |
| Wirt | Rabbit |
| Produktinformation (PDF) | Download |
| MSDS (PDF) | Download |
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