Clone Number: EP268
Immunogen: Unknown or proprietery to MONOSAN and/or its suppliers
Concentration: n/a
Storage buffer: Tris Buffer, pH 7.3-7.7, containing 1% BSA and <0.1% Sodium Azide
Additional info: Sry-related HMG-BOX gene 10, SOX-10, is a transcription factor involved in neural crest and peripheral nervous system development, and acts as a nucleocytoplasmic shuttle protein. SOX-10 is expressed in melanocytic lineages, and is a sensitive marker of melanoma for conventional, and desmoplastic subtypes. In normal tissues, SOX-10 is expressed in melanocytes, and myoepithelial cells.
References: Rehberg S, et al. Mol Cell Biol. 2002; 22:5826-34/Nonaka D, et al. Am J Surg Pathol.2008; 32:1291-8/Nielsen TO, et al. Appl Immunohistochem Mol Morphol. 2012; 20:445-50