Rb1 (Tumor Suppressor Protein) (RB1/2313R), 1mg/mL

Rb1 (Tumor Suppressor Protein) (RB1/2313R), 1mg/mL
Artikelnummer
BTMBNUM2313-50
Verpackungseinheit
50 uL
Hersteller
Biotium

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Description: This antibody recognizes a 105 kDa phosphoprotein, identified as retinoblastoma (Rb) gene product. Its epitope is localized between aa 703-772. It shows no cross reaction with p107 or p130. It specifically stains the nuclei of BT-20 cells and primary human foreskin fibroblast (HFF) cells. It does not stain the Rb-negative BT549 cells. It reacts with the hyperphosphorylated as well as the un (under) phosphorylated form of the Rb protein. Retinoblastoma gene product plays a key role in cell cycle control. It has been identified as a tumor suppressor gene whose loss of its function leads to tumor development. It is widely expressed in a variety of human tissues including breast, esophageal, squamous cell and cervical carcinoma.Primary antibodies are available purified, or with a selection of fluorescent CF® Dyes and other labels. CF® Dyes offer exceptional brightness and photostability. Note: Conjugates of blue fluorescent dyes like CF®405S and CF®405M are not recommended for detecting low abundance targets, because blue dyes have lower fluorescence and can give higher non-specific background than other dye colors.

Conjugate: Purified, BSA-free

Concentration: 1 mg/mL

Storage buffer: PBS, no BSA, no azide

Product Origin: Animal - Oryctolagus cuniculus (domestic rabbit)

Clone: RB1/2313R

Entrez Gene ID: 5925

Immunogen: Recombinant full-length human Rb1 protein

Verified AB Applications: IHC (FFPE) (verified)

Z-Antibody Applications: IHC, FFPE (verified)
Mehr Informationen
Artikelnummer BTMBNUM2313-50
Hersteller Biotium
Hersteller Artikelnummer BNUM2313-50
Verpackungseinheit 50 uL
Mengeneinheit STK
Reaktivität Human, Mouse (Murine)
Klonalität Recombinant
Methode Immunohistochemistry
Isotyp IgG
Wirt Rabbit
Konjugat Unconjugated
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MSDS (PDF) Download