Recombinant Bovine FGG/Fibrinogen gamma chain protein (His tag)

Recombinant Bovine FGG/Fibrinogen gamma chain protein (His tag)
Artikelnummer
ELSPDEB100012-1
Verpackungseinheit
1mg
Hersteller
Elabscience Biotechnology

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Protein Tag: N-His

Uniprot: P12799

Accession: P12799

Background: Together with fibrinogen alpha (FGA) and fibrinogen beta (FGB), polymerizes to form an insoluble fibrin matrix. Has a major function in hemostasis as one of the primary components of blood clots. In addition, functions during the early stages of wound repair to stabilize the lesion and guide cell migration during re-epithelialization. Was originally thought to be essential for platelet aggregation, based on in vitro studies using anticoagulated blood. However, subsequent studies have shown that it is not absolutely required for thrombus formation in vivo. Enhances expression of SELP in activated platelets via an ITGB3-dependent pathway. Maternal fibrinogen is essential for successful pregnancy. Fibrin deposition is also associated with infection, where it protects against IFNG-mediated hemorrhage. May also facilitate the antibacterial immune response via both innate and T-cell mediated pathways.

Bio Acitivity: Not validated for activity

Sequence: Tyr 25-Asp 444

Purity: > 95% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5%-8% trehalose, mannitol and 0.01% Tween 80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 46.1 kDa

Observed MW: 50 kDa
Mehr Informationen
Artikelnummer ELSPDEB100012-1
Hersteller Elabscience Biotechnology
Hersteller Artikelnummer PDEB100012-1
Verpackungseinheit 1mg
Mengeneinheit STK
Reaktivität Cow (Bovine)
Wirt Escherichia Coli
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