Recombinant Human ATXN2 protein (GST tag)

Abbreviation: ATXN2

Target Synonym: Ataxin-2;Spinocerebellar ataxia type 2 protein;Trinucleotide repeat-containing gene 13 protein;ATXN2;ATX2;SCA2;TNRC13

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-GST

UNIProt ID: Q99700

Background: Involved in EGFR trafficking, acting as negative regulator of endocytic EGFR internalization at the plasma membrane.Expressed in the brain, heart, liver, skeletal muscle, pancreas and placenta. Isoform 1 is predominant in the brain and spinal cord. Isoform 4 is more abundant in the cerebellum. In the brain, broadly expressed in the amygdala, caudate nucleus, corpus callosum, hippocampus, hypothalamus, substantia nigra, subthalamic nucleus and thalamus.

Sequence: Leu 460-Ser 600

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100125-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100125-100
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK