Background: platelet receptor Gi24 is a single-pass type I membrane protein; and located at the cell surface. The protein can be cleaved by MMP14; and stimulate MMP14-mediated MMP2 activation. It is participated in the BMP signaling pathway. It also regulates the CD4-pasitive; alpha-beta T cell proliferation; and T cell cytokine production negatively. However; the protein can regulate stem cell differentiation positively.
Sequence: Phe33-Ala194(Asp187Glu)
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4. Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization. Please refer to the specific buffer information in the printed manual.
Endotoxin: < 1.0 EU per ug of the protein as determined by the LAL method.