Recombinant Human Beclin-1 Protein(Trx Tag)

Protein Tag: N-Trx

Uniprot: Q14457

Accession: Q14457

Background: This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants.

Bio Acitivity: Not validated for activity

Sequence: Thr141-Lys450

Purity: > 90% as determined by reducing SDS-PAGE.

Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.

Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.

Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.

Calculated MW: 54 kDa

Observed MW: 60 kDa

• Artikelnummer: ELSPDEH100552-1
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: PDEH100552-1
• Verpackungseinheit: 1mg
• Mengeneinheit: STK
• Reaktivität: Human
• Wirt: Escherichia Coli