Recombinant Human CTNNB1 Protein

Abbreviation: CTNNB1

Target Synonym: Catenin beta-1;Beta-catenin;CTNNB;OK;SW-cl.35;PRO2286

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P35222

Background: Key downstream component of the canonical Wnt signaling pathway. In the absence of Wnt, forms a complex with AXIN1, AXIN2, APC, CSNK1A1 and GSK3B that promotes phosphorylation on N-terminal Ser and Thr residues and ubiquitination of CTNNB1 via BTRC and its subsequent degradation by the proteasome.

Sequence: Met131-Tyr670

Purity: > 85 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100082-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100082-20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK