Recombinant Human ER alpha protein (His tag)

Abbreviation: ER alpha

Target Synonym: Estrogen Receptor α;Estrogen Receptor;ER;ER-Alpha;Estradiol Receptor;Nuclear Receptor Subfamily 3 Group A Member 1;ESR1;ESR;NR3A1

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P03372

Background: Estrogen Receptor is a major ligand-activated transcription factor belonging to the nuclear hormone receptor superfamily. Estrogen Receptor is composed of several domains important for hormone binding, DNA binding, and activation of transcription. The protein localizes to the nucleus where it may form a homodimer or a heterodimer with estrogen receptor 2. Estrogen and its receptors are essential for sexual development and reproductive function, but they also play a role in other tissues such as bone. Estrogen receptors are also involved in pathological processes including breast cancer, endometrial cancer, and osteoporosis. Alternative splicing results in several transcript variants, which differ in their 5' UTRs and use different promoters.

Sequence: Met 297-Ser 554

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100237-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100237-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK