Recombinant Human GLUT6/SLC2A6 protein (GST,His tag)

Abbreviation: GLUT6;SLC2A6

Target Synonym: Solute carrier family 2;facilitated glucose transporter member 6;SLC2A6;Glucose transporter type 6;GLUT6

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-GST & C-His

UNIProt ID: Q9UGQ3

Background: GLUT6 as a functionally uncharacterized transporter that putatively works in inflammatory responses. Inflammatory stimuli increase GLUT6 expression level, although GLUT6-knockout mice exhibit a subtle phenotype to lipopolysaccharide administration. Metabolomics and in vitro analyses show that GLUT6 functions as a glycolysis modulator in inflammatory macrophages. GLUT6 does not mediate glucose uptake and is localized on lysosomal membranes. We conclude that GLUT6 is a lysosomal transporter that is regulated by inflammatory stimuli and modulates inflammatory responses by affecting the metabolic shift in macrophages.

Sequence: Asn 216-Thr 289

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100310-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100310-20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK