Recombinant Human IL-28B/IFN-lambda-3 protein (His tag)

Abbreviation: IL-28B;IFN-lambda-3

Target Synonym: Interleukin-28B;IL-28B;Cytokine Zcyto22;Interferon Lambda-3;Interferon Lambda-4;IFN-Lambda-4;Interleukin-28C;IL-28C;IL28B;IFNL3;IFNL4;IL28C;ZCYTO22

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: Q8IZI9

Background: Interleukin-28B; also known as Cytokine Zcyto22; Interferon lambda-3; Interferon lambda-4; IFNL3; IFNL4; ZCYTO22 and IL28B; is a secreted cytokine which belongs to the IL-28/IL-29 family. IL-28 has also been shown to play a role in the adaptive immune response. IL28B has immunomodulatory activity and up-regulates MHC class I antigen expression. IL28B displays potent antiviral activity and antitumor activity. In addition; IL28B is a ligand for the heterodimeric class II cytokine receptor composed of IL10RB and IL28RA. The ligand/receptor complex seems to signal through the Jak-STAT pathway.

Sequence: Val 22-Val 196

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100260-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100260-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK