Protein Tag: N-Sumo
Uniprot: Q8TAD2
Accession: Q8TAD2
Background: IL17D is a secreted cytokine with homology to the IL-17 family of proteins. IL17D is preferentially expressed in skeletal muscle,brain,adipose tissue,heart,lung,and pancreas. The treatment of endothelial cells with IL17D has been shown to stimulate the production of other cytokines including IL6,IL8 and CSF2/ GM-CSF. The increased expression of IL8 induced by IL17D was found to be NF-kappa B-dependent.
Bio Acitivity: Not validated for activity
Sequence: Ala16-Pro202
Purity: > 90% as determined by reducing SDS-PAGE.
Formulation: Lyophilized from a 0.2 μm filtered solution in PBS with 5% Trehalose and 5% Mannitol.
Reconstitution: It is recommended that sterile water be added to the vial to prepare a stock solution of 0.5 mg/mL. Concentration is measured by UV-Vis.
Endotoxin: < 10 EU/mg of the protein as determined by the LAL method.
Calculated MW: 33.4 kDa
Observed MW: 35-40 kDa
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