Recombinant Human MCP-1 protein (GST tag)

Abbreviation: MCP-1

Target Synonym: C-C motif chemokine 2;HC11;Monocyte chemoattractant protein 1;MCAF;Monocyte chemotactic protein 1;MCP-1;Monocyte secretory protein JE;CCL2

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-GST

UNIProt ID: P13500

Background: The chemokine (C-C motif) ligand 2 (CCL2), also known as monocyte chemoattractant protein (MCP)-1 and small inducible cytokine A2 (SCYA2)), is a small cytokine that belongs to the CC chemokine family responsible for monocyte attraction. Its cognate receptor, CCR2, play a critical role in regulating nociceptive processes during neuropathic pain. Both CCL2 and CCR2 are implicated in induction of autoimmunity. CCL2 recruits monocytes, memory T cells, and dendritic cells to the sites of inflammation produced by either tissue injury or infection. Recently research also showed that CCL2 might be useful as a biomarker of fibrosis as well as a target for therapeutic intervention.

Sequence: Gln 24-Thr 99

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100193-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100193-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK