Recombinant Human PPARG protein(His tag)

Abbreviation: PPARG

Target Synonym: PPAR-gamma;Nuclear receptor subfamily 1 group C member 3;PPAR-γ

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P37231

Background: Nuclear receptor that binds peroxisome proliferators such as hypolipidemic drugs and fatty acids. Once activated by a ligand, the nuclear receptor binds to DNA specific PPAR response elements (PPRE) and modulates the transcription of its target genes, such as acyl-CoA oxidase. It therefore controls the peroxisomal beta-oxidation pathway of fatty acids. Key regulator of adipocyte differentiation and glucose homeostasis. ARF6 acts as a key regulator of the tissue-specific adipocyte P2 (aP2) enhancer. Acts as a critical regulator of gut homeostasis by suppressing NF-kappa-B-mediated pro-inflammatory responses. Plays a role in the regulation of cardiovascular circadian rhythms by regulating the transcription of ARNTL/BMAL1 in the blood vessels.

Sequence: Pro234-Tyr505

Purity: > 80 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100100-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100100-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK