Recombinant Human Rock-2 protein (His tag)

Abbreviation: Rock-2

Target Synonym: Rho kinase 2;Rho-associated;Rho-associated protein kinase 2;ROCK 2;Rock II;Rock2;ROCK2;Rock2m;ROK alpha;ROKalpha

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: O75116

Background: ROCK2/II (Rho-associated protein kinase 2; also Rho-kinase alpha ) is a member of the AGC serine/threonine protein kinase family. ROCK2 is a downstream target of activated RhoA. Its activation results in myosin phosphorylation with subsequent muscle contraction. Human ROCK2 is 1388 amino acids (aa) in length, and appears to be present as a dimer. It contains a protein kinase domain (aa 92?354), a coiled-coil region (aa 429?1131) and a zinc-finger region (aa 1260?1315). Two isoforms show an alternate start site at M686, and a three aa substitution for the N-terminal 444 amino acids.

Sequence: Leu 904-Gly 1140

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100162-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100162-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK