Abbreviation: TIMP3
Target Synonym: HSMRK222;K222TA2;Metalloproteinase inhibitor 3;MIG 5 protein;SFD;TIMP 3;TIMP-3;Tissue Inhibitor of Metalloproteinase 3
Target Species: Human
Expression Host: E.coli
Fusion Tag: N-10His
UNIProt ID: P35625
Background: Complexes with metalloproteinases (such as collagenases) and irreversibly inactivates them by binding to their catalytic zinc cofactor. May form part of a tissue-specific acute response to remodeling stimuli. Known to act on MMP-1, MMP-2, MMP-3, MMP-7, MMP-9, MMP-13, MMP-14 and MMP-15.
Sequence: Cys 24-Asn 144
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.