Recombinant Human TNNC1 protein (His tag)

Abbreviation: TNNC1

Target Synonym: CMD1Z;CMH13;TN-C;TNC;TNNC;Troponin C

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P63316

Background: Troponin I, also known as TNNC1, is part of the troponin complex. This complex contains 3 subunits: troponin I (TnI), troponin T (TnT) and troponin C (TnC). Troponin I is the inhibitory subunit, blocking actin-myosin interactions and thereby mediating striated muscle relaxation. It binds to actin in thin myofilaments to hold the actin-tropomyosin complex in place. Because of it myosin cannot bind actin in relaxed muscle. When calcium binds to the Troponin C it causes conformational changes which lead to dislocation of troponin I and finally tropomyosin leaves the binding site for myosin on actin leading to contraction of muscle.

Sequence: Met 1-Glu 161

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100121-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100121-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK