Recombinant Human TRAPPC8 protein (His tag)

Abbreviation: TRAPPC8

Target Synonym: Trafficking protein particle complex subunit 8;TRAPPC8;Protein TRS85 homolog;KIAA1012

Target Species: Human

Expression Host: E.coli

Fusion Tag: N-His & C-His

UNIProt ID: Q9Y2L5

Background: The transport protein particle (TRAPP) complex was initially identified as a tethering factor for COPII vesicle. Subsequently, three forms (TRAPPI, II, and III) have been found and TRAPPIII has been reported to serve as a regulator in autophagy. This study investigates a new role of mammalian TRAPPIII in ciliogenesis. We found a ciliopathy protein, oral-facial-digital syndrome 1 (OFD1), interacting with the TRAPPIII-specific subunits TRAPPC8 and TRAPPC12. TRAPPC8 is necessary for the association of OFD1 with pericentriolar material 1 (PCM1).

Sequence: Gly 100-Gln 250

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEH100255-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEH100255-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK