Recombinant Mouse HP1alpha protein (His tag)

Abbreviation: HP1α

Target Synonym: HP1 alpha;Antigen p25;CBX5;Chromobox 5;Epididymis luminal protein 25;HEL25;Heterochromatin protein 1;HP1A

Target Species: Mouse

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: Q61686

Background: Component of heterochromatin that recognizes and binds histone H3 tails methylated at 'Lys-9' (H3K9me), leading to epigenetic repression. In contrast, it is excluded from chromatin when 'Tyr-41' of histone H3 is phosphorylated (H3Y41ph). Can interact with lamin-B receptor (LBR). This interaction can contribute to the association of the heterochromatin with the inner nuclear membrane. Involved in the formation of functional kinetochore through interaction with MIS12 complex proteins.

Sequence: Met 1-Ser 191

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEM100072-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEM100072-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK