Recombinant Mouse IFNAR1 Protein (His Tag)

Abbreviation: IFNAR1

Target Synonym: Interferon alpha/beta receptor 1;IFN-R-1 IFN-alpha/beta receptor 1;Cytokine receptor class-II member 1;Cytokine receptor family 2 member 1;CRF2-1;Type I interferon receptor 1;IFNAR

Target Species: Mouse

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P33896

Background: Component of the receptor for type I interferons, including interferons alpha, IFNB1 and IFNW1. Functions in general as heterodimer with IFNAR2 . Type I interferon binding activates the JAK-STAT signaling cascade, and triggers tyrosine phosphorylation of a number of proteins including JAKs, TYK2, STAT proteins and the IFNR alpha- and beta-subunits themselves. Can form an active IFNB1 receptor by itself and activate a signaling cascade that does not involve activation of the JAK-STAT pathway.

Sequence: Glu27-Cyc284

Purity: > 85 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEM100011-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEM100011-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK