Recombinant Mouse MME/CD10/Neprilysin protein (His tag)

Abbreviation: MME;CD10;Neprilysin

Target Synonym: Atriopeptidase;CALLA;Enkephalinase;EPN;NEP;Neprilysin;neprilysin-390;neprilysin-411;SFE;Skin fibroblast elastase

Target Species: Mouse

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: Q61391

Background: CD10, also known as neprilysin, common acute lymphoblastic leukemia antigen (CALLA), or neutral endopeptidase (NEP), is a zinc-dependent transmembrane metallo-endopeptidase. CD10 cleaves peptides at the N-terminal side of hydrophobic amino acid residues and deactivates a variety of signaling peptides. CD10 was shown to be one of the markers for a natural killer cell-restricted progenitor in fetal and adult tissues. Studies also suggest CD10 as a phenotypic marker to distinguish mature neutrophils from immature neutrophils in patients with inflammation. In addition, CD10+GPR77+ carcinoma-associated fibroblasts (CAFs) promote tumor formation and chemoresistance.

Sequence: Met 461-Trp 750

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDEM100075-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDEM100075-20
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK