Recombinant Rabbit IL21 protein(His tag)

Abbreviation: IL-21

Target Synonym: Interleukin-21;IL 21;IL-21

Target Species: Rabbit

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: G1T948

Background: IL21 belongs to the IL-15/IL-21 family. It is a cytokine with immunoregulatory activity. Cytokines are proteinaceous signaling compounds that are major mediators of the immune response. They control many different cellular functions including proliferation, differentiation, and cell survival/apoptosis but are also involved in several pathophysiological processes including viral infections and autoimmune diseases. Cytokines are synthesized under various stimuli by a variety of cells of both the innate (monocytes, macrophages, dendritic cells) and adaptive (T- and B-cells) immune systems. IL21 is expressed in activated CD4-positive T-cells but not in CD8-positive T-cells, B-cells, or monocytes. It may promote the transition between innate and adaptive immunity. IL-21 has been tried as a therapy for alleviating allergic responses. It can significantly decrease pro-inflammatory cytokines produced by T cells in addition to decreasing IgE levels in a mouse model for rhinitis (nasal passage inflammation).

Sequence: Met1-Leu154

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDMO100001-20
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDMO100001-20
• Green Labware: Nein
• Verpackungseinheit: 20 µg
• Mengeneinheit: STK