Recombinant Rat Adrenomedullin/ADM protein (His tag)

Abbreviation: Adrenomedullin;ADM

Target Synonym: ADM precursor;Adrenomedullin;PAMP;Preproadrenomedullin;ProAM N terminal 20 peptide;ProAM N20

Target Species: Rat

Expression Host: E.coli

Fusion Tag: N-His

UNIProt ID: P43145

Background: Adrenomedullin (ADM; also AM) is a secreted, monomeric, 6 kDa member of the Adrenomedullin family of molecules. It is widely expressed, being found in smooth muscle cells, endothelium, adrenal medulla chromaffin cells, fibroblasts and keratinocytes. ADM has multiple functions, including vasodilation, the maintenance of vascular integrity, and the suppression of inflammatory mediator secretion. The ADM preproprecursor is 185 amino acids (aa) in length. It contains a 21 aa signal sequence, a processed 20 aa peptide termed PAMP (aa 22-41), an N-terminal propeptide (aa 45-91), the ADM precursor (amidation is required for maturation) (aa 94 143), and a C-terminal propeptide (aa 150-185). The ADM precursor with a terminal Gly147 circulates naturally with bioactive, mature amidated ADM (aa 94 143).

Sequence: Thr 21-Leu 185

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDER100060-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDER100060-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK