Recombinant Rat IL-6 Protein

Abbreviation: IL-6

Target Synonym: Interleukin-6;IL6;Il-6

Target Species: Rat

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: P20607

Background: Cytokine with a wide variety of biological functions in immunity, tissue regeneration, and metabolism. Binds to IL6R, then the complex associates to the signaling subunit IL6ST/gp130 to trigger the intracellular IL6-signaling pathway. The interaction with the membrane-bound IL6R and IL6ST stimulates 'classic signaling', whereas the binding of IL6 and soluble IL6R to IL6ST stimulates 'trans-signaling'. Alternatively, 'cluster signaling' occurs when membrane-bound IL6:IL6R complexes on transmitter cells activate IL6ST receptors on neighboring receiver cells.

Sequence: Met1-Thr211

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4., 5% trehalose, 5% mannitol, 0.01% tween-80.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDMR100004-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDMR100004-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK