Abbreviation: IL1A;IL-1F1
Target Synonym: BAF;Hematopoietin-1;IL1 alpha;IL-1 alpha;IL1;IL1A;IL-1A;IL1-ALPHA;IL1F1;IL-1F1;IL1F1hematopoietin-1;interleukin 1;alpha;interleukin-1 alpha;LAF;LEM;preinterleukin 1 alpha;pro-interleukin-1-alpha
Target Species: Rat
Expression Host: E.coli
Fusion Tag: N-His
UNIProt ID: P16598
Background: IL-1 alpha (Interleukin-1 alpha) is a cytokine that is induced during microbial exposure and promotes the release of multiple inflammatory mediators and acute phase proteins. It also supports hematopoietic stem cell expansion, promotes neutrophil mobilization from the bone marrow, and promotes osteoclast formation. IL-1 alpha signals through a receptor complex composed of IL-1 RI and IL-1 RAcP. It also binds the decoy receptor IL-1 RII which associates with IL-1 RAcP but does not transduce signaling.
Sequence: Ser 115-Ser 270
Purity: > 95 % as determined by reducing SDS-PAGE.
Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.
Endotoxin: Please contact us for more information.