Recombinant Rat Interleukin-2/IL-2 Protein (His Tag)

Abbreviation: Interleukin-2;IL-2

Target Synonym: Aldesleukin;IL 2;IL-2;IL2;IL2;Interleukin 2;Interleukin-2;Involved in regulation of T cell clonal expansion;Lymphokine;POIL2;T Cell Growth Factor;T-cell growth factor;TCGF

Target Species: Rat

Expression Host: HEK293 Cells

Fusion Tag: C-His

UNIProt ID: P17108

Background: Interleukin-2(IL-2)is a O-glycosylated four α-helix bundle cytokine that has potent stimulatory activity for antigenactivated T cells. It is expressed by CD4+ and CD8+ T cells, γδ T cells, B cells, dendritic cells, and eosinophils. Mature rat IL-2 shares 66% and 73% amino acid sequence identity with human and mouse IL-2,respectively. The receptor for IL-2 consists of three subunits that are present on the cell surface in varying preformed complexes. IL-2 is a powerful immunoregulatory lymphokine produced by T-cells in response to antigenic or mitogenic stimulation. IL-2/IL-2R signaling is required for T-cell proliferation and other fundamental functions that are essential for the immune response. IL-2 stimulates growth and differentiation of B-cells, NK cells, lymphokine-activated killer cells, monocytes, macrophages and oligodendrocytes.

Sequence: Ala 21-Gln 155

Purity: > 95 % as determined by reducing SDS-PAGE.

Formulation: Lyophilized from sterile PBS, pH 7.4.
Normally 5 % - 8 % trehalose, mannitol and 0.01% Tween80 are added as protectants before lyophilization.
Please refer to the specific buffer information in the printed manual.

Endotoxin: Please contact us for more information.

• Artikelnummer: ELSPDMR100011-100
• Hersteller: Elabscience Biotechnology
• Hersteller Artikelnummer: ELA-PDMR100011-100
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK