RPSA antibody (RPSA/2699)

RPSA antibody (RPSA/2699)
Artikelnummer
GTX04349-100
Verpackungseinheit
100 μg
Hersteller
GeneTex

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Clone Name: RPSA/2699

Light Chain: Kappa

Application Note: WB: 1-2 µg/ml. ICC/IF: 1-2 µg/ml. IHC-P: 1-2 µg/ml. FACS: 1-2 µg/ml. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 33

Form: Liquid

Buffer (with preservative): 10mM PBS, 0.05% BSA (Please contact us for PBS only format), 0.05% Sodium azide.

Concentration: 0.2 mg/ml (Please refer to the vial label for the specific concentration.)

Background: Laminins, a family of extracellular matrix glycoproteins, are the major noncollagenous constituent of basement membranes. They have been implicated in a wide variety of biological processes including cell adhesion, differentiation, migration, signaling, neurite outgrowth and metastasis. Many of the effects of laminin are mediated through interactions with cell surface receptors. These receptors include members of the integrin family, as well as non-integrin laminin-binding proteins. This gene encodes a high-affinity, non-integrin family, laminin receptor 1. This receptor has been variously called 67 kD laminin receptor, 37 kD laminin receptor precursor (37LRP) and p40 ribosome-associated protein. The amino acid sequence of laminin receptor 1 is highly conserved through evolution, suggesting a key biological function. It has been observed that the level of the laminin receptor transcript is higher in colon carcinoma tissue and lung cancer cell line than their normal counterparts. Also, there is a correlation between the upregulation of this polypeptide in cancer cells and their invasive and metastatic phenotype. Multiple copies of this gene exist, however, most of them are pseudogenes thought to have arisen from retropositional events. Two alternatively spliced transcript variants encoding the same protein have been found for this gene. [provided by RefSeq, Jul 2008]

Uniprot ID: P08865

Antigen Species: Human

Immunogen: Recombinant full-lengthhuman RPSA protein

Purification: Protein A/G purified

Conjugation: Unconjugated

Full Name: ribosomal protein SA
Mehr Informationen
Artikelnummer GTX04349-100
Hersteller GeneTex
Hersteller Artikelnummer GTX04349-100
Green Labware Nein
Verpackungseinheit 100 μg
Mengeneinheit STK
Reaktivität Human
Klonalität Monoclonal
Methode Immunofluorescence, Immunohistochemistry (paraffin), Western Blotting, Immunocytochemistry, Fluorescence-Activated Cell Sorting (FACS)
Isotyp IgG1
Human Gene ID 3921
Wirt Mouse
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