SAHA (Vorinostat), CAS 149647-78-9

HDAC inhibitor

Product Type: Inhibitor

CAS No.: 149647-78-9

MolecularFormula: C14H20N2O3

Molecular Weight: 264,3

Source: Synthetic

Purity: >98% (TLC), NMR conforms

Solubility: Soluble in 50 mg/ml DMSO, or 2 mg/ml Ethanol

Appearance: White Solid

PubChem CID: 5311

Scientific Background: Potent and selective histone deacetylase inhibitor. Induces apoptosis in a variety of tumor cell lines. Synergizes with kinase inhibitors to kill CNS tumor cells. Cell permeable.

References: 1. Vrana J.A., et al., (1999) Oncogene. 18: 7016.2. Butler L.M., et al., (2002) Proc. Natl. Acad. Sci. USA. 99: 11700.3. Tang Y., et al., (2012) Cancer Biol. Ther. 2012 13(7): 567-574.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-359-250MG
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-359-250MG
• Verpackungseinheit: 250 mg
• Mengeneinheit: STK