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Encompassing Amino Acids: 27-347
Description: Human secreted Sialic Acid Binding Ig Like Lectin 6 (Siglec6)-Fc fusion protein, also known as CD33 Antigen-Like 1 (CD33L1) and Obesity-Binding Protein 1 (OBBP1), GenBank Accession No. NM_001245, a.a. 27-347, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag, expressed in a HEK293 cell expression system and enzymatically biotinylated using Avi-tag™ technology. Biotinylation is confirmed to be ≥90%. MW = 64 kDa. This protein runs at a higher molecular weight due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_001245
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: C-terminal Fc-Avi-tag
Uniprot: O43699
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Brinkman-Van der Linden, E.C.M., et al., Glycobiology. 2007 Sep 8; 17(9):922-931.
2. Patel, N. et al., JBC. 1999 Aug 6; 274:22729-22738.