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Encompassing Amino Acids: 17-363
Description: Human secreted Siglec8, also known as Sialic Acid Binding Ig Like Lectin 8, and SAF2, GenBank Accession No. NM_014442, a.a. 17-363, fused at the C-terminus of the Fc portion of human IgG1, with C-terminal Avi-tag™ expressed in a HEK293 cell expression system. MW = 67 kDa. This protein runs at a higher MW by SDS-PAGE due to glycosylation.
Format: Aqueous buffer solution
Formulation: 8 mM Phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol.
Genbank: NM_014442
Storage Stability: At least 6 months at -80°C.
Supplied As: Aqueous buffer solution.
Tags: C-terminal Avi-tag
Uniprot: Q9NYZ4
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Bochner, B.S., et al., JBC. 2005 Feb; 280: 4307-4312.
2. Nutku, E., et al., Blood. 2003 Jun; 101(12): 5014-5020