SIRP-α (CD172a), His-tag (Human) Recombinant

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Applications: Useful for studying protein binding and screening small molecules.

Description: Signal regulatory protein-alpha (SIRP-α), also known as Tyrosine-protein phosphatase non-receptor type substrate 1, CD172a, Bit, and MyD-1, GenBank Accession No. NM_080792, a.a. 27-370, with C-terminal His-tag, MW 38.4 kDa*, expressed in a HEK293 expression system. This protein acts as a receptor for CD47; a.a. 27-370 correspond to the extracellular portion of SIRP-α. *Note: SIRP-α is heavily glycosylated, resulting in apparent higher molecular weight.

Format: Aqueous buffer solution

Formulation: 40 mM Tris-HCl, pH 8.0, 110 mM NaCl, 2.4 mM KCl, and 20% glycerol

Genbank: NM_080792

Host Cell Line: HEK293

Storage Stability: At least 6 months at -80°C.

Tags: C-terminal His-tag

Uniprot: P78324

Warnings: Avoid freeze/thaw cycles. Protein may be diluted to ≥ 100 µg/ml in PBS + glycerol and stored at -80°C.

Biosafety Level: Not applicable (BSL-1)

References: 1. Hatherley, D., et al., Mol. Cell, 2008, 31:266-77
2. Baba, N., et al., J. Exp. Med., 2013, 210(6):1251-63

• Artikelnummer: BPS71145-2
• Hersteller: BPS Bioscience
• Hersteller Artikelnummer: 71145-2
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Wirt: Human