Sodium Valproate, CAS 1069-66-5

HDAC inhibitor

Product Type: Inhibitor

CAS No.: 1069-66-5

MolecularFormula: C8H15NaO2

Molecular Weight: 166,2

Source: Synthetic

Purity: >98% (TLC), NMR conforms

Solubility: Soluble in 50 mg/ml Water

Appearance: White Solid

PubChem CID: 16760703

Scientific Background: Histone deacetylase inhibitor (IC50=400 µM). Demonstrates neuroprotective, anticancer and anti-inflammatory activity. Inhibits Aβ production and neuritic plaque formation in Alzheimer's mouse models. Clinically useful anticonvulsant.

References: 1. Phiel C.J., et al. (2001) J. Biol. Chem. 276: 36734.2. Kim H.J., et al. (2007) J. Pharmacol. Exp. Ther. 321: 892.3. Qing H., et al. (2008) J. Exp. Med. 205: 2781.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSIH-357-5G
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SIH-357-5G
• Verpackungseinheit: 5 g
• Mengeneinheit: STK