Sulfotyrosine Antibody, Clone 12B11: Biotin

Mouse Anti-Sulfotyrosine Monoclonal IgG1

Target: Sulfotyrosine

Conjugate: Biotin

Product Type: Monoclonal

Clone Number: 12B11 (Formerly sold as 7C5)

Immunogen: Synthetic Sulfotyrosine conjugated to Keyhole Limpet Hemocyanin (KLH).

Purification: Protein G Purified

Storage Buffer: PBS pH 7.4, 50% glycerol, 0.09% Sodium azide *Storage buffer may change when conjugated

Concentration: 1 mg/ml

Specificity: Specific for sulfated tyrosine residues on various proteins. Does not detect free Sulfotyrosine. Does not cross-react with phosphotyrosine.

Scientific Background: Tyrosine sulfation is a common post-translational protein modification catalyzed by tyrosylprotein sulfotransferase (TPST) (1). Sulfotyrosines mediate interactions between hirudin and thrombin, P-selectin glycoprotein ligand-1 and P-selectin, and von Willebrand factor and factor VIII. Tyrosine sulfation of certain receptors is required for several viruses and parasites to enter their hosts.

References: 1. Lee, R.W., Huttner W.B. (1983). J Biol Chem. 258(18):11326-34.

Field of Use: Not for use in humans. Not for use in diagnostics or therapeutics. For in vitro research use only.

• Artikelnummer: STRSMC-522D-BI
• Hersteller: Stressmarq Biosciences
• Hersteller Artikelnummer: SMC-522D-BI
• Green Labware: Nein
• Verpackungseinheit: 100 µg
• Mengeneinheit: STK
• Reaktivität: Various species
• Klonalität: Monoclonal
• Methode: Immunofluorescence, Western Blotting, ELISA, Immunohistochemistry, Immunocytochemistry
• Isotyp: IgG1
• Wirt: Mouse