Application Note: WB: 1:1000 - 1:3000. IHC-P: 1:50-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 54
Form: Liquid
Buffer (with preservative): PBS, 150mM NaCl, 50% Glycerol, 0.02% Sodium azide.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The Hedgehog signaling pathway plays an important role in early human development. The pathway is a signaling cascade that plays a role in pattern formation and cellular proliferation during development. This gene encodes a negative regulator of the hedgehog signaling pathway. Defects in this gene are a cause of medulloblastoma. Alternative splicing results in multiple transcript variants.[provided by RefSeq, May 2010]
Uniprot ID: Q9UMX1
Antigen Species: Human
Immunogen: A synthesized peptide derived from human SUFU(Accession Q9UMX1), corresponding to amino acid residues M1-L29.
Purification: Purified by antigen-affinity chromatography
Conjugation: Unconjugated
Full Name: SUFU negative regulator of hedgehog signaling