Target Synonym: LCX; Cxxc6; AA517754; BB001228; D10Ertd17; mKIAA1676; D10Ertd17e; 2510010B09Rik
Storage: Store at -20°C Valid for 12 months. Avoid freeze / thaw cycles.
Background: Enables methylcytosine dioxygenase activity. Involved in several processes, including dendrite morphogenesis; inner cell mass cell differentiation; and protein O-linked glycosylation. Acts upstream of or within DNA demethylation; regulation of DNA methylation; and regulation of genetic imprinting. Located in nucleus. Is expressed in several structures, including brain; early conceptus; embryo ectoderm; lower urogenital tract; and reproductive system. Orthologous to human TET1 (tet methylcytosine dioxygenase 1).
Buffer: PBS with 0.05% proclin300,50% glycerol,pH7.3.
Immunogen: Recombinant fusion protein of mouse TET1
Dilution: IHC 1:50-1:200
Calculated MW: 219kDa
Observed MW: 250KDa
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