Application Note: WB: 1:300-1:5000. ICC/IF: 1:50-1:200. IHC-P: 1:200-1:400. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Calculated MW: 56
Form: Liquid
Buffer (with preservative): 0.01M TBS, 1% BSA, 50% Glycerol, 0.03% Proclin300.
Concentration: 1 mg/ml (Please refer to the vial label for the specific concentration.)
Background: The protein encoded by this gene forms a heteromeric complex with type II TGF-beta receptors when bound to TGF-beta, transducing the TGF-beta signal from the cell surface to the cytoplasm. The encoded protein is a serine/threonine protein kinase. Mutations in this gene have been associated with Loeys-Dietz aortic aneurysm syndrome (LDAS). Multiple transcript variants encoding different isoforms have been found for this gene. [provided by RefSeq, Aug 2008]
Uniprot ID: P36897
Antigen Species: Human
Immunogen: KLH conjugated synthetic peptide derived from human TGF-beta R1 (301-400aa)
Purification: Protein A purified
Conjugation: Unconjugated
Full Name: transforming growth factor beta receptor 1