Clone Name: HMV323
Light Chain: Kappa
Product Description: This antibody was validated on 76 different Normal Tissues by IHC-P.
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Application Note: IHC-P: 1:100-1:200. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.
Specificity/Sensitivity: This antibody was raised against human TIGIT Intracellular domain.
Form: Liquid
Buffer (with preservative): PBS, 2% BSA, 0.025% ProClin 300.
Concentration: 0.25 mg/ml
Background: This gene encodes a member of the PVR (poliovirus receptor) family of immunoglobin proteins. The product of this gene is expressed on several classes of T cells including follicular B helper T cells (TFH). The protein has been shown to bind PVR with high affinity; this binding is thought to assist interactions between TFH and dendritic cells to regulate T cell dependent B cell responses.[provided by RefSeq, Sep 2009]
Uniprot ID: Q495A1
Antigen Species: Human
Immunogen: Recombinant protein encompassing a sequence within the Intracellular domain of human TIGIT. The exact sequence is proprietary.
Purification: Affinity purified by Protein A.
Conjugation: Unconjugated
Full Name: T cell immunoreceptor with Ig and ITIM domains