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Applications: Useful for studying protein binding and for screening small molecules and antibodies.
Description: Recombinant human TGIT (T-cell immunoreceptor with Ig and ITIM domain), encompassing amino acids 22-141. This construct contains a C-terminal Fc region. The recombinant protein was affinity purified.
Endotoxin Level: <1 EU/µg
Format: Aqueous buffer solution
Formulation: 8 mM phosphate, pH 7.4, 110 mM NaCl, 2.2 mM KCl, and 20% glycerol
Genbank: NM_173799
Host Cell Line: HEK293
Purity: ≥85%
Storage Stability: At least 6 months at -80°C.
Tags: C-terminal Fc fusion (Human IgG1)
Uniprot: Q495A1
Warnings: Avoid freeze/thaw cycles.
Biosafety Level: Not applicable (BSL-1)
References: 1. Yu, X., et al., Nat. Immunol. 2009; 10(1): 48-57.
2. Stanietsky, N., et al., Proc. Natl. Acad. Sci. (USA). 2009; 106(42): 17858-17863.