TNF Receptor II antibody (GT1237)

Clone Name: GT1237

Application Note: WB: 1:500 - 1:2000. *Optimal dilutions/concentrations should be determined by the researcher.Not tested in other applications.

Calculated MW: 48

Form: Liquid

Buffer (with preservative): PBS, 0.05% BSA, 50% Glycerol, 0.02% Sodium azide.

Concentration: 0.48 mg/ml (Please refer to the vial label for the specific concentration.)

Background: The protein encoded by this gene is a member of the TNF-receptor superfamily. This protein and TNF-receptor 1 form a heterocomplex that mediates the recruitment of two anti-apoptotic proteins, c-IAP1 and c-IAP2, which possess E3 ubiquitin ligase activity. The function of IAPs in TNF-receptor signalling is unknown, however, c-IAP1 is thought to potentiate TNF-induced apoptosis by the ubiquitination and degradation of TNF-receptor-associated factor 2, which mediates anti-apoptotic signals. Knockout studies in mice also suggest a role of this protein in protecting neurons from apoptosis by stimulating antioxidative pathways. [provided by RefSeq, Jul 2008]

Uniprot ID: P20333

Antigen Species: Human

Immunogen: A synthesized peptide derived from human TNF Receptor II

Purification: Purified by antigen-affinity chromatography

Conjugation: Unconjugated

Full Name: TNF receptor superfamily member 1B

• Artikelnummer: GTX02834-100
• Hersteller: GeneTex
• Hersteller Artikelnummer: GTX02834-100
• Green Labware: Nein
• Verpackungseinheit: 100 μl
• Mengeneinheit: STK
• Reaktivität: Human, Mouse (Murine), Rat (Rattus)
• Klonalität: Monoclonal
• Methode: Western Blotting
• Isotyp: IgG
• Human Gene ID: 7133
• Wirt: Rabbit